How to Give a B12 Injection: Step By Step Instructions HOW TO SELF INJECT B12 AT HOME with Dr. Tyler Rogers If you've been prescribed vitamin B12 shots or exploring at home wellness, this step by step guide will walk you through how B12 Injection sites + How to use B12 Shots Safely Hi Dr. Tony here! If you give yourself injectionstestosterone, estrogen, insulin, peptides, or B12these are 3 of my favorite tips to make them almost painless. Tip 1: Insert the needle quickly, then How to draw up B12 injections How to self inject intramuscular vitamin B12 Overview Guy's and St Thomas' NHS Foundation Trust